Recruiting

Sexual Dysfunction in Women With Multiple Sclerosis (MS)

ClinicalTrials.gov IDNCT07193823

PhaseNot Applicable

Enrollment140

SponsorEge University

Age25 Years

SexFEMALE

I'm interested View official listing

Conditions studied

Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting, Fatigue in Multiple Sclerosis, Sexual Disfunction, Cognitive Dysfunction, Depression, Anxiety, Overactive Bladder, Fatigue

About this study

Sexual dysfunction in women with multiple sclerosis (MS) is an important yet often overlooked problem. The primary objective of this study is to investigate the prevalence of sexual dysfunction in female patients diagnosed with MS. The secondary objective is to evaluate the relationship between sexual dysfunction and fatigue, depression, anxiety, overactive bladder symptoms, and cognitive dysfunction. For this purpose, the following validated instruments will be used: the Female Sexual Function Index (FSFI) to assess sexual dysfunction, the Brief International Cognitive Assessment for MS (BICAMS) to evaluate cognitive function, the Hospital Anxiety and Depression Scale (HADS) to assess depression and anxiety, the Fatigue Severity Scale (FSS) to measure fatigue, and the Overactive Bladder Questionnaire (OAB-V8) to evaluate overactive bladder symptoms.

Primary outcomes

Prevalence of sexual dysfunction in female patients with multiple sclerosis (At enrollment (Baseline, cross-sectional assessment))

Eligibility information

Inclusion Criteria: * Female patients aged 25-50 years * Literate and able to comprehend written and spoken instructions * Diagnosed with relapsing-remitting form of multiple sclerosis * Having a continuous/regular sexual partner * Expanded Disability Status Scale (EDSS) score ≤ 5 * At least 3 months since the last relapse * Sexually active within the past 3 months * Spasticity level \< grade 2 according to the Modified Ashworth Scale Exclusion Criteria: * Pregnancy * Illiteracy or inability to understand spoken or written instructions * Absence of a continuous/regular sexual partner * Expanded Disability Status Scale (EDSS) score \> 5 * Not sexually active within the past 3 months * Spasticity level ≥ grade 2 according to the Modified Ashworth Scale

Study locations

Ege University Faculty of Medicine, Department of Neurology, Izmir, Bornova 35100 Turkey (Türkiye)

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.