Recruiting
Randomized Controlled Trial of Two Mobile Health Strategies to Manage Postpartum Hypertension
A multicenter randomized trial that will compare the effectiveness of two postpartum blood pressure (BP) management strategies in improving blood pressure and cardiac function and increasing patient engagement and feeling of control over one's health
ClinicalTrials.gov IDNCT07209254
PhaseNA
Enrollment770
SponsorJennifer Lewey, MD, MPH
Age18 Years and older
SexFEMALE
Conditions studied
Hypertension, Pregnancy Induced
About this study
A multicenter randomized trial that will compare the effectiveness of two postpartum blood pressure (BP) management strategies in improving blood pressure and cardiac function and increasing patient engagement and feeling of control over one's health
Interventions
- Other: High-touch blood pressure management — Twelve weeks of text-based home blood pressure monitoring with BP self-management and team-based care
- Other: Low-touch blood pressure management — 10 days of text-based home blood pressure monitoring
Primary outcomes
- Mean diastolic blood pressure (DBP) (12 months postpartum)
Eligibility information
Inclusion Criteria:
* Age ≥18 years
* Delivery within 14 days
* Diagnosis of preeclampsia or gestational hypertension with or without severe features during pregnancy or within 14 days postpartum
* Initiation of blood pressure medication prior to hospital discharge and up to 14 days postpartum
* English or Spanish speaking (able to read/understand consent and instructions)
* Has phone texting capabilities
Exclusion Criteria:
* Diagnosis of chronic hypertension prior to delivery (would therefore include super imposed preeclampsia)
* Pre-existing cardiovascular disease (including prior myocardial infarction, stroke, heart failure with reduced ejection fraction, ventricular tachycardia, prior cardiac arrest, pacemaker, severe valvular heart disease, or prior cardiac surgery)
* Chronic kidney disease (stage 3 or higher)
* Using ≥3 BP medications at time of enrollment
Study locations
- NYU Langone Health, New York, New York 10022 United States
- The Ohio State University, Columbus, Ohio 43210 United States
- University of Pennsylvania, Philadelphia, Pennsylvania 19104 United States
Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-10-05.