Recruiting
Cardiovascular Protection After Preeclampsia With Enalapril
The purpose of this study is to learn if postpartum women are willing to be randomized to different blood pressure medicines after delivery and how that affects blood pressure in women with hypertensive disorders of pregnancy.
ClinicalTrials.gov IDNCT07222852
PhasePHASE3
Enrollment60
SponsorWomen and Infants Hospital of Rhode Island
Age18 Years
SexFEMALE
Conditions studied
Preeclampsia, Hypertensive Disorder of Pregnancy, Hypertension, Gestational Hypertension, Gestational Hypertension After Childbirth
About this study
The purpose of this study is to learn if postpartum women are willing to be randomized to different blood pressure medicines after delivery and how that affects blood pressure in women with hypertensive disorders of pregnancy.
Interventions
- Drug: Enalapril — First-line anti-hypertensive treatment with enalapril
- Other: Standard treatment — First-line anti-hypertensive treatment per standard of care
Primary outcomes
- Feasibility of enrollment (4 months)
- Feasibility of retention (4 months)
Eligibility information
Inclusion Criteria:
* Postpartum individuals
* ≥18 years old
* Hypertensive disorder of pregnancy
* Enrolled in Women and Infants Hospital Hypertension Equity remote monitoring program.
Exclusion Criteria:
* Maternal cardiac disease
* Individuals with pre-pregnancy hypertension or diabetes
* Allergy or contraindication to enalapril
Study locations
- Women and Infants Hospital, Providence, Rhode Island 02906 United States
Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.