Cardiovascular Risk Assessment in Young Women After Index Pregnancy With and Without Placental Complications

Conditions studied

Cardiovascular (CV) Risk, Preeclampsia (PE), Fetal Weight

About this study

In this project, the investigators aim to study how all these factors determine the cardiovascular status of a total of 1,800 mothers, 3 to 6 years after delivery. In addition, the investigators want to assess whether lifestyle and living conditions after childbirth may improve or worsen this imprint, since women often prioritize their families over themselves, making it more difficult to maintain a healthy lifestyle that could reduce their cardiovascular risk. Furthermore, the investigators will evaluate how environmental exposures influence their health, as well as explore potential strategies for prediction and prevention. The goal is to develop an easy-to-use algorithm or test that allows women and their physicians to assess this risk, ideally in the form of a mobile app. Although predictive algorithms for cardiovascular health already exist, most have been developed using predominantly male or older populations, and none have taken into account pregnancy-related events or environmental exposure - both of which are key determinants of women's cardiovascular health.

Primary outcomes

• Hypertension (3-6 years after index pregnancy)
• Abnormal cardiac function (3-6 years after index pregnancy)
• Biochemical cardiac markers (3-6 years after index pregnancy)
• Coronary artery disease (3-6 years after index pregnancy)
• Other cardiovascular major events (3-6 years after index pregnancy)

Eligibility information

Study locations

• Hospital de la Santa Creu i de Sant Pau, Barcelona, 08025 Spain