Recruiting
Study of the Progression of Chronic Cardiovascular Conditions
This study will collect physiologic data in patients with cardiovascular conditions and observe the natural history of those conditions for research purposes.
ClinicalTrials.gov IDNCT07420907
PhaseNot Applicable
Enrollment5000
SponsorProlaio
Age18 Years
SexALL
Conditions studied
Cardiovascular Disease (CVD), Heart Failure, Aortic Stenosis, Aortic Stenosis Disease, Hypertension, Hypertension (HTN), Hypertrophic Cardiomyopathy Patients, Hypertrophic Cardiomyopathy Without Obstruction, Hypertrophic Cardiomyopathy, Obstructive, Dilated Cardiomyopathy (DCM), Dilated Cardiomyopathy, Dilated Cardiomyopathy, Familial
About this study
This study will collect physiologic data in patients with cardiovascular conditions and observe the natural history of those conditions for research purposes.
Primary outcomes
- Longitudinal Assessment of Clinical Status (Baseline through each 90-day cycle)
- Longitudinal Assessment of Clinical Status (Baseline through each 90-day cycle)
- Longitudinal Assessment of Clinical Status (Baseline through each 90-day cycle)
- Longitudinal Assessment of Clinical Status (Baseline through each 90-day cycle)
Eligibility information
Inclusion Criteria:
* 18 years of age and older
* Ability to understand study assessments and give informed consent to data collection
* Ability to comply with the study protocol
* Ability to understand and respond to instructions in English
* Has diagnosis of qualifying Cardiovascular Disease(s), including but not limited to: HF, AS, HCM, HTN, DCM, etc. Additional CVD may be included at discretion of the investigators.
* Resides in the United States
Exclusion Criteria:
* Allergy to adhesive used in biosensor patch
* Life-threatening disease process outside of area under study, such as actively treated cancer or being actively considered for organ pre-transplant (such as hepatic failure; end-stage renal disease).
* Severe CVD defined by hospital admission for cardiac diagnosis within 30 days of enrollment or documentation of NYHA functional class IV
* \-- For participants who do not qualify due to this exclusion, and have not been hospitalized within 30 days of enrollment, they may reapply to enroll in the study
* Self-reported weight of 400 pounds or greater
Study locations
- Prolaio, Chicago, Illinois 60606 United States
Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.