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Dynamic and Isometric Strength Training in Older Adults With Hypertension

This feasibility study aims to evaluate the effects of dynamic strength training and isometric strength training on cardiovascular health indicators, mental health, and neuromuscular fitness in older adults with hypertension. Participants will be randomly assigned to one of the two training modalities and will complete supervised exercise sessions throughout the intervention period. The study will provide preliminary evidence regarding the safety, acceptability, and potential impact of each training modality on…

ClinicalTrials.gov IDNCT07448818

PhaseNA

Enrollment60

SponsorRaphael Mendes Ritti Dias

Age60 Years

SexALL

I'm interested View official listing

Conditions studied

Hypertension, Elderly (People Aged 65 or More)

About this study

Interventions

Behavioral: Dynamic Strength Training — The experimental group will perform dynamic strength exercises targeting major muscle groups, progressing in intensity and volume over the 6 weeks. Exercises include 8 major muscle group movements, initially 2 sets of 15 repetitions (Borg 4-6), progressing to 3 sets of 10 repetitions (Borg 5-7) from week 5. Participants will also be advised to perform non-supervised walking 3-5 times per week for \~30 minutes at moderate intensity.
Behavioral: Isometric Strength Training — The experimental group will perform isometric strength exercises targeting major muscle groups, progressing in intensity and volume over the 6 weeks. Exercises include 8 major muscle group contractions, initially 2 sets of 60 seconds (Borg 4-6), progressing to 3 sets of 40 seconds (Borg 5-7) from week 5. Participants will also be advised to perform non-supervised walking 3-5 times per week for \~30 minutes at moderate intensity.
Behavioral: No supervised intervention Control — This group serves as a control and will not perform any structured exercise program.

Primary outcomes

Recruitment rate (Baseline and 6 weeks)
Adherence to training sessions (During 6 weeks)
Retention rate (During 6 weeks)
Fidelity to exercise protocol (Duiring 6 weeks)
Acceptability of the intervention (During 6 weeks)
Occurrence of adverse events (During 6 weeks)

Eligibility information

Inclusion criteria: * Diagnosis of arterial hypertension and currently taking antihypertensive medication * Age 60 years or older * Resting blood pressure below 160/95 mmHg * No high cardiovascular risk according to the American College of Sports Medicine criteria (for participants with type 2 diabetes, glycemic control with fasting glucose \<100 mg/dL and postprandial glucose \<140 mg/dL) * Not participating in a structured exercise program for more than three months * No cognitive or functional limitations that prevent participation in the exercise program Exclusion Criteria * Presence of acute illnesses, such as influenza, sinusitis, gastroenteritis, urinary tract infection, fever, inflammatory processes, or any clinical condition requiring rest or that may compromise safety during assessments or training. * Decompensated clinical conditions, including: Blood pressure spikes, Chest pain, Uncontrolled arrhythmias, Shortness of breath at rest, Asthma exacerbations, Decompensated diabetes mellitus, characterized by Persistently elevated blood glucose levels (fasting glucose \> 180 mg/dL or postprandial glucose \> 250 mg/dL) * Irregular use of medication * Any unstable clinical condition or condition that represents additional risk for the practice of physical exercise.

Study locations

Uninove, São Paulo, São Paulo 01525-000 Brazil

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.