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UBM Evaluation After Combined Deep Sclerectomy With Trabeculotomy in Primary Open Angle Glaucoma

Primary open-angle glaucoma is a chronic optic neuropathy that often requires surgical intervention when medical treatment fails. Deep sclerectomy is a non-penetrating glaucoma surgery that aims to reduce intraocular pressure while minimizing complications. When combined with trabeculotomy, additional aqueous outflow may be achieved. Ultrasound biomicroscopy (UBM) allows detailed imaging of the anterior segment and provides valuable information about postoperative anatomical changes that cannot be assessed…

ClinicalTrials.gov IDNCT07454447
PhaseNot Applicable
Enrollment30
SponsorMinia University Hospital
AgeNo minimum reported
SexALL
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Conditions studied

Primary Open Angle Glaucoma (POAG)

About this study

Primary open-angle glaucoma is a chronic optic neuropathy that often requires surgical intervention when medical treatment fails. Deep sclerectomy is a non-penetrating glaucoma surgery that aims to reduce intraocular pressure while minimizing complications. When combined with trabeculotomy, additional aqueous outflow may be achieved. Ultrasound biomicroscopy (UBM) allows detailed imaging of the anterior segment and provides valuable information about postoperative anatomical changes that cannot be assessed clinically. This observational study aims to evaluate UBM findings after combined deep sclerectomy with trabeculotomy in patients with primary open-angle glaucoma and to correlate these findings with clinical outcomes.

Interventions

Primary outcomes

Eligibility information

Inclusion Criteria: * Diagnosis of primary open-angle glaucoma (POAG), including juvenile open-angle glaucoma (JOAG). * Patients who underwent combined deep sclerectomy with trabeculotomy. * Clear media allowing adequate ultrasound biomicroscopy imaging. * Written informed consent obtained from the patient . Exclusion Criteria: * Secondary glaucomas (e.g., neovascular, uveitic, traumatic, or angle-closure glaucoma). * Previous glaucoma filtering surgery in the studied eye. * Coexisting ocular pathology affecting UBM assessment (e.g., severe corneal opacity, scleral pathology).

Study locations

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.