Environment, Inflammation and Metabolic Diseases Study

Conditions studied

Endocrine Disease, Metabolic Disorders, Hypertension, Diabetes Mellitus

About this study

The aim is to establish an effective and practical early warning model for endocrine and metabolic diseases based on an environmental-gene-protein panoramic network, to uncover new mechanisms underlying the onset and progression of these diseases, and to screen for novel therapeutic targets.

Interventions

• Other: observe — A single observational cohort of study participants undergoing baseline biochemical screening for autonomous aldosterone secretion (AAS). No experimental interventions or treatments are administered. All participants receive standard clinical care and undergo standardized baseline assessments, including measurement of plasma aldosterone concentration (PAC) and plasma renin concentration (PRC) for AAS classification, as well as collection of demographic, clinical, biochemical, anthropometric data and biospecimens for proteomic analysis.

Primary outcomes

• The prevalence of autonomous secretion of aldosterone (The follow-up period from baseline enrollment to the completion of follow-up examinations was approximately 5 years)

Eligibility information

Study locations

• The First Affiliated Hospital of Chongqing Medical University, Chongqing, China