Clinical trials / NCT07608055
Recruiting

Clinical, Oncologic, and Metabolic Effects of Pancreatic Mass Loss After Pancreatectomy in Non-Diabetic Patients

This study will examine how removal of part or all of the pancreas affects blood sugar control, metabolism, and clinical outcomes over time. The study will include adults without diabetes before surgery who undergo pancreatic surgery as part of routine clinical care at Fondazione Policlinico Universitario A. Gemelli IRCCS. Researchers will study whether participants develop diabetes after surgery and whether this risk changes according to the type of pancreatic resection. Information from routine clinical care…

ClinicalTrials.gov IDNCT07608055
PhaseNot Applicable
Enrollment579
SponsorFondazione Policlinico Universitario Agostino Gemelli IRCCS
Age18 Years
SexALL
I'm interested View official listing

Conditions studied

Pancreatectomy, Diabetes Mellitus Type 2, Pancreatic Neoplasms

About this study

This study will examine how removal of part or all of the pancreas affects blood sugar control, metabolism, and clinical outcomes over time. The study will include adults without diabetes before surgery who undergo pancreatic surgery as part of routine clinical care at Fondazione Policlinico Universitario A. Gemelli IRCCS. Researchers will study whether participants develop diabetes after surgery and whether this risk changes according to the type of pancreatic resection. Information from routine clinical care, metabolic tests, imaging, and pancreatic tissue samples collected during surgery may be used for research analyses.

Primary outcomes

Eligibility information

Inclusion Criteria: * Adult patients (≥18 years) * No diabetes mellitus at baseline * Undergoing partial, near-total, or total pancreatectomy at the study center * Availability of clinical and metabolic data according to study component * Written informed consent for the prospective component Exclusion Criteria: * Diabetes mellitus at baseline * Age \<18 years * Missing key clinical data precluding eligibility assessment or primary outcome evaluation * Refusal or inability to provide informed consent for the prospective component, where applicable

Study locations

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.