Hydration Intervention to Decrease Side Effects Associated With GLP - 1 RA Therapy

Conditions studied

Obesity & Overweight, Type 2 Diabetes, Type 2 Diabetes (Adult Onset), Obesity Type 2 Diabetes Mellitus, Dehydration

About this study

This is a 17 - week study consisting of a one - week run - in period and a 16 - week intervention. The 16 - week pilot interventions aims to increase hydration in those beginning GLP - 1 RA therapy. Investigators aim to increase hydration to potentially decrease side effect severity, amount of side effects, and drug discontinuation associated with GLP - 1 RA therapy. The investigators are piloting to assess feasibility and preliminary efficacy of the intervention through examining participant retention, participant feedback, researcher and participant adherence to protocols, impact on hydration biomarkers, and participant reported GLP - 1 RA side effects.

Interventions

• Behavioral: Hydration Plus — The hydration plus intervention aims to increase hydration through employing the following behavior change strategies/techniques: coaching (consisting of goal setting, making a plan, and coping planning), positive feedback, and utilize a contingency management payment schedule wherein participant earned amount hinges on them meeting their goal.
• Behavioral: Control — Participants randomly assigned to the control group will receive information on hydration and will receive prompts to drink.

Primary outcomes

• Acceptability of hydration plus (At week 16, which is the end of the program.)
• Feasibility of Intervention (At week 16, which is the end of the program.)
• Change in physiological hydration score (Baseline (week 0) to week 16 (post - program))
• Change in perceived hydration level (Week -1 (run - in week) to week 16 (end of program))

Eligibility information

Study locations

• State University of New York at Buffalo, South Campus, Buffalo, New York 14214 United States