Sleep More, Stress Less: 90-Day Trial of Neuralli Mood
This decentralized, single-arm study evaluates the effects of 90 days of daily Neuralli Mood supplementation on perceived stress, sleep disturbance, mood, anxiety, depressive symptoms, happiness, and occupational burnout in adults experiencing stress or occasional sleep disruption. Participants serve as their own controls, completing validated self-report measures before beginning supplementation and again after the 90-day intervention, with safety and adherence check-ins during the study.
Conditions studied
Psychological Stress, Sleep Disturbance, Anxiety Symptoms, Depressive Symptoms, Occupational Burnout
About this study
This decentralized, single-arm study evaluates the effects of 90 days of daily Neuralli Mood supplementation on perceived stress, sleep disturbance, mood, anxiety, depressive symptoms, happiness, and occupational burnout in adults experiencing stress or occasional sleep disruption. Participants serve as their own controls, completing validated self-report measures before beginning supplementation and again after the 90-day intervention, with safety and adherence check-ins during the study.
Interventions
- Dietary Supplement: Neuralli Mood — Two acid-resistant capsules taken once daily for 90 days. Each daily dose contains 30 billion CFU of L. plantarum PS128 and 20 billion heat-treated cells of L. paracasei PS23. Other ingredients include microcrystalline cellulose, hypromellose, pectin, glycerol, silica, and magnesium stearate.
Primary outcomes
- Change in Depression Anxiety and Stress Scales-21 Stress Subscale Score (Baseline before the first dose and end of the 90-day supplementation period)
- Change in PROMIS Sleep Disturbance Score (Baseline before the first dose and end of the 90-day supplementation period)
Eligibility information
Study locations
- Efforia - Decentralized United States Study, New York, New York 10003 United States
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-10-28.