Recruiting
A Study to Assess Brillouin Hydration Mapping for the Evaluation of Ocular Tissues and Diseases
The overall goal of this study is to develop Brillouin microscope as a novel tool for measuring biomechanical and hydration properties of human tissues in vivo.
ClinicalTrials.gov IDNCT07780890
PhaseNot Applicable
Enrollment90
SponsorMassachusetts General Hospital
Age20 Years
SexALL
Conditions studied
Fuchs Endothelial Corneal Dysfunction, Open Angle Glaucoma (OAG), Dry Eye Disease (DED), Keratoconus, Lasik Eye Surgery
About this study
The overall goal of this study is to develop Brillouin microscope as a novel tool for measuring biomechanical and hydration properties of human tissues in vivo.
Primary outcomes
- Number of subjects to successfully complete Brillouin measurement without serious unanticipated adverse events related to application of the device. (Through completion of the single study visit, approximately 1-2 hours)
Eligibility information
Inclusion Criteria:
* Healthy volunteers with normal eyes
* Visual acuity between +2 to -6 diopters
Exclusion Criteria:
* History of refractive or cataract surgery
* History of ocular disease
* Active non-ophthalmic systemic disease
Study locations
- Massachusetts General Brigham, Boston, Massachusetts 02114 United States
Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.
Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-09-27.