Clinical trials / NCT07781306
Recruiting

PrOspEctive Metastases Imaging (POEM)

This is a non-interventional, observational study with an optional interventional biobanking activity. Liver metastases of patients undergoing partial hepatectomy will be sampled completely while respecting the orientation used for medical imaging, in order to correlate the histopathological growth patterns in a 3D-map with the imaging characteristics. The full pathological sampling will only use remnant tissue.

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ClinicalTrials.gov IDNCT07781306
PhaseNot Applicable
Enrollment50
SponsorCancer Research Antwerp
Age18 Years and older
SexALL
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Conditions studied

Liver Metastases, Colorectal Cancer, Breast Cancer

About this study

This is a non-interventional, observational study with an optional interventional biobanking activity. Liver metastases of patients undergoing partial hepatectomy will be sampled completely while respecting the orientation used for medical imaging, in order to correlate the histopathological growth patterns in a 3D-map with the imaging characteristics. The full pathological sampling will only use remnant tissue.

Primary outcomes

Eligibility information

Inclusion Criteria: 1. ≥ 18 years old. 2. Patients with liver metastatic colorectal or breast carcinoma undergoing a surgical excision of the liver metastases 3. Therapy-naive patients as well as patients with neo-adjuvant therapy are eligible for inclusion 4. Willingness of the patient to participate in this study demonstrated by signed written informed consent Exclusion Criteria: 1. Patients without MRI or CT of the liver prior to surgery 2. Time interval between medical imaging, CT and/or MRI is more than 12 weeks (nb: time interval is preferably less than 4 weeks but this is not an exclusion criterium) 3. Prior radiofrequency ablation (RFA) or transarterial chemoembolization (TACE) on the liver metastasis that would be operated

Study locations

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-11-15.