Clinical trials / NCT07833930
Recruiting

Incidence and Clinical Features of Breakthrough Pain After Brachial Plexus Block in Diabetic Patients

This observational study aims to determine the incidence and clinical characteristics of rebound-breakthrough pain after ultrasound-guided brachial plexus block in adult patients with type 2 diabetes mellitus. Adult patients undergoing elective upper-extremity surgery are divided into a type 2 diabetes group and a non-diabetic control group. Baseline clinical data and pain-related outcomes are collected after nerve block. This work may provide evidence for optimizing perioperative pain management for diabetic…

ClinicalTrials.gov IDNCT07833930
PhaseNot Applicable
Enrollment216
SponsorSecond Hospital of Shanxi Medical University
Age18 Years – 80 Years
SexALL
I'm interested View official listing

Conditions studied

Postoperative Pain

About this study

This observational study aims to determine the incidence and clinical characteristics of rebound-breakthrough pain after ultrasound-guided brachial plexus block in adult patients with type 2 diabetes mellitus. Adult patients undergoing elective upper-extremity surgery are divided into a type 2 diabetes group and a non-diabetic control group. Baseline clinical data and pain-related outcomes are collected after nerve block. This work may provide evidence for optimizing perioperative pain management for diabetic patients receiving brachial plexus block.

Primary outcomes

Eligibility information

Inclusion Criteria: * Aged 18 years or older * Undergoing elective upper-extremity surgery * Planned for ultrasound-guided brachial plexus block with 0.375% ropivacaine * Able to cooperate with pain assessment and follow-up within 48 hours after block * Written informed consent obtained Exclusion Criteria: * Allergy or contraindication to amide-type local anesthetics * Pre-existing peripheral neuropathy of the affected upper limb * Chronic regular use of opioids before surgery * Coagulopathy or infection at the block puncture site * Cognitive dysfunction unable to complete NRS pain evaluation * Pregnancy or lactation * Incomplete clinical data expected during follow-up

Study locations

Before you participate: Varda Clinical is an independent discovery tool, not the study sponsor or a medical provider. Eligibility can only be determined by the official study team. Discuss potential risks and benefits with a qualified healthcare professional.

Source: ClinicalTrials.gov. Record last refreshed by Varda Clinical: 2026-10-26.